Search results for "None L. Ivings"

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Ether-Lipids Are Involved in Retinal Vegf Expression and in Postnatal Hyaloid Vessel Regression

2009

Purpose:Ether-lipids are phospholipids that represent about 13% of retinal lipids and whose exact functions remain unknown. However, the preferential esterification of polyunsaturated fatty acids (PUFAs) at the sn-2 position of ether-lipids and their liberation by an ether-lipid-specific phospholipase A2 suggest their involvement in cell signaling processes. Based on the data showing the persistence of the hyaloid vasculature in ether-lipid-deficient mice (DAPAT-/- mice, Rodemer et al Hum Mol Genet 2003), we further investigated the molecular mechanisms by which ether-lipids may regulate hyaloid vessels regression during post-natal development. Methods:C57BL/6 mice were treated at birth eit…

None C. FourgeuxNone C. JoffreNone L. Bretillonvascular endothelial growth factorNone. Support: None lipids vascular endothelial growth factor developmentC. FourgeuxNone A.M. BronC. JoffreNone B. PasquisCommercial Relationships: N. AcarDevelopmentLipidsC.P. Creuzot-GarcherL. IvingsNone W.W. Just[SDV.AEN] Life Sciences [q-bio]/Food and NutritionA.M. Bron[SDV.MHEP.OS] Life Sciences [q-bio]/Human health and pathology/Sensory OrgansNoneL. BretillonNone C.P. Creuzot-GarcherB. PasquisW.W. JustNone. Support: None lipidsNone L. Ivings
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